Proton Transfer Reaction Mass Spectrometry (PTR-MS) is a new real-time and non-invasive sampling technique which has been used used for headspace analysis above urine and fluids obtained from the gut during colonscopy, in-vitro discrimination of cancerous and non-cancerous cell lines, and for studies of emissions from skin.
PTR-MS has also been used for investigations involving occupational health exposure in medical environments.
Other medical-related work has been associated with investigating chemical compounds emitted from various bacterial cultures, with a potential ultimate objective of being able to provide a sensitive analytical technique to identify in-vivo infection quickly, and thereby enable the correct antibiotic treatment to be administered more rapidly.
However, by far the largest number of investigations have been associated with breath analysis.
The aim of this meeting is to introduce the technique of PTR-MS and to illustrate its use in breath analysis as a method for the detection of trace chemicals (sub ppbv –ppbm) in the breath that can be used for diagnostics and therapy control.
Dr Philipp Sulzer, Ionicon Analytik GmbH, Innsbruck Austria
Professor Jochen Schubert, University of Rostock, Germany
Dr. Wilfried Szymczak, Helmholtz Zentrum Munchen,